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A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors
adulthepatocellular-carcinomahpv-related-carcinomanon-small-cell-lung-cancersoft-tissue-sarcomasolid-tumor
Assessment of the efficacy and safety of Regorafenib and Avelumab in patients with advanced or metastatic solid tumors (ten cohorts), once the Recommanded Phase II Dose (RP2D) has been determined (phase I trial). Assessement of the efficacy and safety of a low-dose of regorafenib (80mg/day) with avelumab in patients with advanced or metastatic colorectal tumors.
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