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A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body

Otsuka Pharmaceutical Development & Commercialization, Inc. · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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autoimmune-diseaserheumatoid-arthritissystemic-lupus-erythematosussystemic-sclerosis
This first-in-human study evaluates the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of HBM7020. The study will enroll healthy participants at low doses, followed by participants with moderate to severe autoimmune diseases with predominant B-cell involvement. Eligible participants include patients with systemic lupus erythematosus (SLE), systemic sclerosis (SSc), Sjögren's disease (SjD), and rheumatoid arthritis (RA).
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