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A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006)

Merck Sharp & Dohme LLC · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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hematologic-malignanciessmall-lymphocytic-lymphoma
Researchers are looking for new ways to treat people with B-cell cancers. In this trial, researchers will look at chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). These are blood cancers that affect B-cells in the blood, bone marrow, or lymph nodes. The goals of this trial are to learn about: * The safety of MK-1045 and if participants tolerate it. Tolerate means participants will receive trial treatment unless they need to stop treatment due to health problems. * The number of participants who respond. Respond means the number of cancer cells goes down or signs of cancer go away.
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