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Mechanisms of Refractory Hypertension (High and Low Salt Diet)

University of Alabama at Birmingham · 2015
ClinicalTrials.gov · Datasets · License: Public Domain · 2015
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hypertension
The purpose of the study is to test the hypothesis that persistent fluid retention and high sympathetic output contributes to the development of refractory hypertension (HTN). The investigators will determine, in a cross-over assessment of high and low salt diets, if dietary sodium restriction reduces 24-hr ambulatory BP in patients with refractory HTN. Moreover, the investigators will determine if dietary sodium restriction lessens the severity of obstructive sleep apnea (OSA) in patients with refractory HTN.
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