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Modular Synthesis of O‑Containing Mono- and Dispiro-Scaffolds: From Simple Alkenes to Targeted Functionalization of Natural Products

Pavel A. Konkin (24961599) et al.
Figshare · Datasets · License: CC BY-NC 4.0
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biochemistrybiotechnologycancercell-biologygeneticsimmunologymolecular-biologypharmacology
We report an efficient and modular synthetic platform for the assembly of structurally diverse O-containing mono- and dispirocycles, leveraging the Zr-catalyzed cycloalumination of alkenes (Dzhemilev reaction) as the key complexity-generating step. This strategy involves the sequential transformatio
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