HAL (France)
open access
Brain Clearance of Contrast Agent in Intravenous DCE ‐ MRI Is Measurable and Cannot Be Explained by Clearance Across the BBB Alone
Purpose To determine the feasibility of measuring brain clearance of gadolinium contrast agent using standard intravenous DCE‐MRI acquisitions and evaluate the contribution of blood–brain barrier (BBB) and non‐BBB clearance routes. Methods Uptake and extended Tofts models were fit to DCE‐MRI data fr
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