Acta Interna: The Journal of Internal Medicine
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Ex vivo Generation of Platelets from Umbilical Cord Blood Hematopoietic Stem Cells with Amniotic Membrane Mesenchymal Stem Cells Support
ABSTRACTBackground: Platelet refractoriness is a major problem among patients requiring repeated transfusion. Production of less immunogenic platelets is required to overcome this problem. Umbilical cord blood (UCB) is rich in hematopoietic stem cells (HSC), which may serve as a potential source of
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