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A comparative molecular dynamics study of methylation state specificity of JMJD2A

Koc University Digital Collections · Papers · License: CC BY 4.0
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chromatinmechanicsmultidisciplinary-sciencesproteinsreceptorrecognitionsimulations
Histone modifications have great importance in epigenetic regulation. JMJD2A is a histone demethylase which is selective for di- and trimethyl forms of residues Lys9 and Lys36 of Histone 3 tail (H3K9 and H3K36). We present a molecular dynamics simulations of mono-, di- and trimethylated histone tail
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