Repositorio de Universidad Autónoma de Chile.
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Fenofibrate-a pparα agonist-increases alcohol dehydrogenase levels in the liver: Implications for its possible use as an ethanol-aversive drug [Fenofibrato-un agonista de pparα-incrementa los niveles de la alcohol deshidrogenasa hepática: Implicaciones para su posible uso como una droga aversiva al etanol]
After ethanol consumption, disulfiram increases blood-acetaldehyde levels, generating an aversive reaction that deters alcohol drinking. Given the major secondary effects of disulfiram, finding other effective drugs to reduce alcohol consumption in individuals with alcohol-use-disorder is highly des
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