Repositorio de Universidad Autónoma de Chile.
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Conjugates of γ 3-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease
Alzheimer disease is a multifactorial pathology and the development of new multitarget neuroprotective drugs is promising and attractive. We synthesized a group of original compounds, which combine in one molecule I 3-carboline fragment of dimebon and phenothiazine core of methylene blue (MB) linked
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