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Produção de L-asparaginase II recombinante de Erwinia carotovora em cultivos de Escherichia coli em batelada alimentada
Biopharmaceutical drugs are mainly recombinant proteins produced by biotechnological tools. Currently on the market L-asparaginase preparations, derived either from Escherichia coli or Erwinia chrysanthemi, have been used as a therapeutic agent on the effective treatment of acute lymphoblastic leuke
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