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Resposta imune a peptídeos derivados da imunoglobulina: da tolerância à auto-imunidade
The interaction between a B cell and a primed T cell, in the T-B border, leads to a germinal center reaction, where an antigen specific B cell increases the affinity and specificity for the antigen. After the generation of the high affinity and specificity, some clones differentiate into antibody pr
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