Efeito da temperatura na enzima 2-trans-enoil-ACP (CoA) redutase (EC 1.3.1.9) de Mycobacterium tuberculosis em complexo com o NADH: um estudo por simulação pela dinâmica molecular

Temperature can interfere with protein structure and function, affecting its ability to bind to other molecules, its conformational microstates distribution, as well as the rate of its enzymatic reactions. Since the mid-20th the in silico or computer experiments have increasingly been used in differ