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Caracterização biofísico-química da enzima Orotato Fosforibosiltransferase (OPRT, EC 2.4.2.10) de Mycobacterium tuberculosis H37Rv: modelo para o desenvolvimento de novas drogas anti-tuberculose
Tuberculosis is a chronic infectious disease mainly caused by Mycobacterium tuberculosis that requires urgent new efforts towards its treatment and cure face the emergence of drug-resistant strains, its world spreading, the increasing number of infected patients among immune compromised populations,
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