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A enzima chiquimato quinase (EC 2.7.1.71) de Mycobacterium tuberculosis como alvo para o desenvolvimento de drogas

Rosado, Leonardo Astolfi
Repositório PUCRS · Papers
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biologia-molecularenzimas
Tuberculosis remains as one of the main cause of mortality worldwide due to a single infectious agent, Mycobacterium tuberculosis. The aroK-encoded Mycobacterium tuberculosis Shikimate Kinase (MtSK), shown to be essential for survival of bacilli, catalyzes the phosphoryl transfer from ATP to the car
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