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Efeito do tratamento com enalapril sobre a hepatoxicidade induzida pelo acetaminofeno em camundongos
Introduction: Acetaminophen (APAP) is a potent antipyretic and analgesic agent, with weak anti-inflammatory effects. Despite its efficacy, the use of elevated doses of APAP is associated with severe hepatotoxicity. It has been suggested that treatment with angiotensin-converting enzyme (ACE) inhibit
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