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A influência dos polimorfismos do gene MDR1 na resposta virológica e imunológica no tratamento com Efavirenz durante os seis primeiros meses em pacientes HIV positivos
Drug transporters are increasingly recognized to be important on drug disposition and therapeutic response. P-glycoprotein, encoded by the human MDR1 (ABCB1) gene, is of particular clinical relevance in that this transporter has broad substrate specificity, including a variety of structurally diverg
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