Estudo do papel dos receptores purinérgicos P2X7 em processos inflamatórios cutâneos em modelos in vitro e in vivo

The irritant contact dermatitis (ICD) is a non-allergic inflammatory reaction of the skin that occurs independently of the T cells participation. ICD is caused by exposure to low molecular weight chemicals and it is initiated by damage or activation of epidermal cells which trigger the activation of