Repositorio de Universidad Autónoma de Chile.
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DOCK2 couples with LEF-1 to regulate B cell metabolism and memory response
Dedicator of cytokinesis 2 (DOCK2) is essential for the B cell differentiation, BCR signaling and humoral immune response. However, the role of DOCK2 in the memory response of B cell is unknown. By using two DOCK2 deficient patients, we found that the memory B cells were decreased and the early acti
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