Repositorio de Universidad Autónoma de Chile.
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Inhibition of IL-2 production by novel small molecules using building blocks from reduced chalcones and a substituted proline
Background: Immunosuppressants are a class of drugs that can inhibit the immune response, mainly through the inhibition of IL-2 production, among other mechanisms. The most studied representatives of this class of therapeutic agents are Cyclosporin- A, FK506, and Rapamycin. Due to the structural com
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