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The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming

Koc University Digital Collections · Papers
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cancercell-biologydifferentiationexpressiongenerationmicrornasmouse
Reprogramming of fibroblasts to induced pluripotent stem cells (iPSCs) entails a mesenchymal to epithelial transition (MET). While attempting to dissect the mechanism of MET during reprogramming, we observed that knockdown (KD) of the epithelial-to-mesenchymal transition (EMT) factor SNAI1 (SNAIL) p
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