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The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis

Koc University Digital Collections · Papers · License: CC BY 4.0
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diseasegene-expressionmicemousemultidisciplinary-sciencesperiodproteintime
Circadian clock is known to adapt to environmental changes and can significantly influence cognitive and physiological functions. In this work, we report specific behavioral, cognitive, and sleep homeostatic defects in the after hours (Afh) circadian mouse mutant, which is characterized by lengthene
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