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C-Abl is not activated in DNA damage-induced and Tap63-mediated oocyte apoptosis in human ovary

Koc University Digital Collections · Papers · License: CC BY 4.0
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cell-biologychemotherapyfertilityin-vitro
There is a controversy in literature as to whether c-Abl is crucial for the induction of TAp63-mediated apoptosis and whether that inhibition of c-Abl with imatinib, which was designed to inhibit the oncogenic kinase BCR-ABL and c-kit, protects oocytes from chemotherapy-induced apoptosis in mice. No
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