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The glycosylation site of myelin oligodendrocyte glycoprotein affects autoantibody recognition in a large proportion of patients

Koc University Digital Collections · Papers · License: CC BY 4.0
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glycosylationimmunologymass-spectrometrymedicineneurology
Autoantibodies to myelin oligodendrocytes glycoprotein (MOG) are found in a fraction of patients with inflammatory demyelination and are detected with MOG-transfected cells. While the prototype anti-MOG mAb 8-18C5 and polyclonal anti-MOG responses from different mouse strains largely recognize the F
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