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Low soluble drug encapsulation based on architecture of layer-by-layer assembly for longer circulation time and targeted therapy
A combined effect of sonication and layer-by-layer assembly (LbL) enhances the solubility of many poorly soluble inorganic and organic materials by forming stable particles with ca. 200 nm size and up to 90 wt% of loading. The entire method is reproducible, easy-to-handle, and flexible for varying s
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