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Gene synthesis, cloning, expression, purification and biophysical characterization of the C2 domain of human tensin
Tensin is a large "docking" protein found in the adhesive junctions of animal cells and recruited early in the development of cell-substrate contacts. There it binds to the cytoplasmic domain of integrin β1 and caps the barbed ends of filamentous actin. This forms a rational basis for its implicatio
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