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Lattice Radiation Therapy Versus Conventional Radiation Therapy for the Palliation of Large Tumors

University Health Network, Toronto · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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The goal of this randomized, phase III trial is to to determine if Spatially Fractionated Lattice Radiotherapy (SFRT) known as LATTICE therapy, leads to a greater reduction in pain or discomfort compared with conventional Radiation Therapy (RT) in patients with large tumours. This is evaluated by assessing if a greater proportion of patients who receive RT with SFRT will have an improvement in pain/discomfort at 30 days defined using the International Consensus Pain Response (ICPR) compared with those treated with conventional RT.
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