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Normal Values of Parameters of Thrombin Generation in Function of Different Tissue Factor Concentrations

Centre Hospitalier Universitaire de Saint Etienne · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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bloodhealthy-volunteersplasma
The thrombin generation assay (TGA) is a good tool for measuring clot formation in plasma.TGA using Calibrated Automated Thrombography method, enables the quantification of thrombin concentrations in platelet-rich plasma (PRP) and in platelet-poor plasma (PPP).According to the clinical context, different TF(Tissue Factor) concentrations (1, 5 and 10 pM) can be used to trigger the coagulation cascade.The aim of the study is to determine the normal values of TG (Thrombin Generation) in fresh PRP and in PPP with different TF concentrations.
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