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Tolerance Through Mixed Chimerism (Sip-Tego)

Tatsuo Kawai, MD, PhD · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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kidney-failurekidney-transplanttolerance
This is an open-label, single-institution study to assess the safety and the efficacy of the Sip-Tego regimen for the induction of donor-specific immunologic unresponsiveness to a renal allograft. The investigators propose to treat 6 adult subjects in end-stage renal disease (ESRD) who do not demonstrate evidence of prior sensitization.
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