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Phase IB/II of CPX-351 for Relapse Prevention in AML

Georgetown University · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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acute-myeloid-leukemiaremission
This is a phase IB/II study with a 3+3 dose de-escalation study design. Patients will continue maintenance treatment with CPX-351 for 6 cycles on D1 and D3, as long as patient remains in CR. The dose de-escalation will be one dose given on D1 only, every 28 days pending toxicity. The maximum tolerated dose will be used for the phase II expansion portion of the study.
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