HAL (France)
open access
Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation
Abstract Hu antigen R (HuR) is a central RNA-binding protein regulating cell dedifferentiation, proliferation, and survival, which are well-established hallmarks of cancer. HuR is frequently overexpressed in tumors correlating with tumor malignancy, which is in line with a role for HuR in tumorigene
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