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When Genomic Masking Priors Fail to Transfer: Strong Variant Prediction, Weak Functional Generation

Hu, Susu et al.
arXiv (All) · Papers
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machine-learning
Bidirectional discrete diffusion model appears naturally suited to genomic modeling because it can reconstruct missing sequence from both flanks. We developed GenDA (Genomic Density-optimized Absorbing Diffusion) under the additional hypothesis that entropy-guided span placement would concentrate re
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