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Agentic BAIM-LLM Evaluation (ABLE): Benchmarking LLM Use of Protein Design Tools

Cai, Bryce et al.
arXiv (All) · Papers
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artificial-intelligencecomputers-and-societyquantitative-methods
We introduce ABLE, a benchmark for evaluating LLM agents' ability to use biological AI models (BAIMs), such as ProteinMPNN and AlphaFold3, in dual-use protein design workflows. ABLE assesses agent performance through a set of tasks spanning structure retrieval, sequence generation, and design valida
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