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NIX-mediated mitophagy regulate metabolic reprogramming in phagocytic cells during Mycobacterial infection
RNASeq analysis of PBMCs from treatment naïve TB patients and healthy controls revealed that M. tuberculosis (Mtb) infection dysregulates several metabolic pathways and upregulates BNIP3L/NIX receptor mediated. mitophagy. Analysis of publicly available transcriptomic data from the NCBI-GEO database
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