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Is Involucrin Has a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study

Benha University · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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Vitamin D3 plays important role in keratinocyte differentiation and had been used recently in verruca vulgaris. Aim of the work: To assess the expression of involucrin in verrucae vulgaris before and after injection of vitamin D3. Subjects and Methods: This study included 60 patients with verrucae vulgaris subjected to intralesional injection of vitamin D3 at three weeks interval for a maximum of five sessions. Immunohistochemical assessment of involucrin was done before and after injection and compared to skin biopsies from 30 healthy individuals
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