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Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination

Merus B.V. · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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colorectal-canceresophageal-squamous-cell-carcinomagastric-cancerhead-and-neck-cancerhead-and-neck-squamous-cell-carcinomansclc
A phase 1/2 open-label multicenter study will be performed with an initial dose escalation part to determine the MTD and/or the RP2D of MCLA-129 in monotherapy or in combination in patients with NSCLC, HNSCC, GC/GEJ, ESCC, or other solid tumors and who are treatment naïve or have progressed after receiving prior therapy for advanced/metastatic disease.
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