Conceptio › Archive › ClinicalTrials.gov
ClinicalTrials.gov public full text Public Domain

Sperm Separation Efficiency to Maximize Pregnancy Rates: MACS vs. FERTILE Chip

Vida Recoletas Sevilla · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
Open Source ↗
infertilitymale
The goal of this observational study is to compare clinical outcomes of two techniques for sperm cell sorting, microfluidic sorting and magnetic activated cell sorting (MACS) technique, in males with high DNA fragmentation within an assisted reproductive treatment. The main questions it aims to answer are: * Does microfluidic sorting improve pregnancy rate compared to MACS? * Does microfluidic sorting improve fertilization rate compared to MACS? * Does microfluidic sorting improve implantation rate compared to MACS? * Does microfluidic sorting improve blastocyst development rate compared to MACS? Participants will deposit an eyaculate sample that will be analyzed for DNA fragmentation using a aliquot, then split in two to perform MACS and the microfluidic sorting. Both will be tested for DNA fragmentation (aliquotes) and used for the ICSI treatment with donor oocytes. Researchers will compare both techniques to see if the selection of the best functional spermatozoa with less DNA fragmentation and clinical outcomes improve.
Conceptio Open Archive

Analyze & explore related research in Conceptio

Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.

This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗

Related documents

Record · ID 981293
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive