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Platform Trial in Stage 1 Diabetes: Comparing Golimumab vs Placebo

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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The goal of this clinical trial is to learn if golimumab is effective at preventing progression to Stage 2 diabetes in participants with presymptomatic Type 1 Diabetes. The expected duration of this study is approximately 6 years. Participants will: * Take golimumab or placebo injections monthly for the duration of the study or until they are diagnosed with either stage 2 or stage 3 Type 1 Diabetes * Visit a study clinic every 6 months for Oral Glucose Tolerance Tests (OGTTs) and other tests until the end of the study
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