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Spontaneous Breathing Trials Using Pressure Support or T-Piece in Overweight and Obese Patients

Taipei Medical University Hospital · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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mechanical-ventilationnaoverweightrespiratory-failure
This study aims to find out which method of spontaneous breathing trial (SBT) better helps overweight and obese ICU patients prepare for extubation, which is the removal of the breathing tube. The two methods being compared are pressure support ventilation (PSV) and the T-piece. Participants are adults with a body mass index (BMI) of 25 or higher who have been on a breathing machine (invasive mechanical ventilation) for more than 24 hours. Before removing the breathing tube, participants will be randomly assigned to receive either a PSV or a T-piece trial for 1 hour. After that, doctors will decide if they are ready for extubation. The main question this study wants to answer is: Which method leads to a higher rate of successful extubation-defined as not needing to be reintubated within 72 hours?
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