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Elucidating the Role of Matrix Viscoelasticity on CD8+ T cell 3D migration

Liu, Xiaoya
eScholarship · Papers
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bioengineeringbiomedical-engineeringcell-migrationcellular-biologyimmunologyviscoelasticity
CD8+ T cells are the primary cytotoxic immune cells that are capable of directly killing cancer cells; however, their tumor-killing potential in solid tumors is often limited by insufficient infiltration into the tumor microenvironment. Recent findings suggest that the limited cytotoxic capacity of
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