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Developing a Human Cerebral Organoid Epilepsy Model for Studying Live 4D Mitochondrial Dynamics in Response to Ketogenic Diet Treatment

Modolo, Andre Caldas
eScholarship · Papers
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biologycellular-biologycrispr-cas9epilepsyneurosciences
Approximately 30% of epilepsy patients experience intractable epilepsy, where traditional pharmacological therapies fail to provide seizure relief. Although challenging to sustain, patients often rely on the high-fat, low-carbohydrate ketogenic diet (KD) as a viable alternative for managing seizures
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