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The role of F-box protein FBXA-11 in regulating thermotolerance in Caenorhabditis elegans
In the nematode Caenorhabditis elegans, a stress/immune response pathway called the Intracellular Pathogen Response (IPR) increases resistance to proteotoxic stress. In mutants with constitutive IPR activation, a CUL-6 cullin-RING ubiquitin ligase complex was previously shown to protect the host fro
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