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Down Syndrome Induced Molecular and Cellular disruption during neurodevelopment

Lin, Hung-Hsiu
eScholarship · Papers
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biology
Down syndrome (DS), caused by the triplication of chromosome 21, results in various physical, intellectual, and neurodevelopmental abnormalities. Despite extensive research, the precise molecular mechanisms and pathways disrupted by trisomy 21 during brain development remain largely unknown due to t
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