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Estimating Causal Treatment Effects in Placebo-Controlled Randomized Clinical Trials When High Placebo Response is Anticipated
In placebo-controlled randomized clinical trials (RCTs), the placebo response significantly modifies treatment effects and diminishes the intention-to-treat (ITT) treatment effect, $Δ_{ITT}$. This study presents a novel two-stage framework for estimating the standardized causal treatment effect, $Δ_
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