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The COP9 signalosome subunit CSN1 regulates glioblastoma stem cell growth

Samir Assaf et al.
PLOS · Papers · License: CC BY 4.0
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hepatocellular-carcinomaphosphorylation
The COP9 signalosome is composed of 8 subunits (CSN1-CSN8) and plays a key role in regulating the activity of the ubiquitin-proteasome system by modulating Cullin-RING ubiquitin ligases. While the function of the COP9 signalosome in regulating protein homeostasis is well established, little is know
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