Zenodo (CERN)
open access
CC BY 4.0
Pathogenic stromal cell-state convergence is transcriptional, not heritable: a genetic-causality audit of a pan-disease atlas, with one exception at the endothelial-protective axis
A pan-disease atlas of pathogenic stromal cell states showed that five lineage-restricted programs — an activated matrix-secretory myofibroblast, an SPP1/TREM2 macrophage, an inflammatory fibroblast, and two endothelial programs (endothelial-to-mesenchymal transition and loss of a BMP/KLF2-
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