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Insulin-based Strategies to Prevent Hypoglycemia During Exercise

McGill University Health Centre/Research Institute of the McGill University Health Centre · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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exercisehypoglycemianatype-1-diabetestype-1-diabetes-mellitus
It has been reported that insulin basal rate reduction initiated at exercise onset can reduce the hypoglycemic risk during exercise. However, another potentially more efficient strategy to prevent exercise-induced hypoglycemia could be to reduce insulin basal rate a certain time prior to exercise. The objective of this study will be to compare the efficacy of two strategies to prevent exercise-induced hypoglycemia during a 60-minute exercise at moderate intensity: 1) reduce insulin basal rate 40 minutes prior to exercise; 2) reduce insulin basal rate 90 minutes prior to exercise.
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