alzheimer-s-disease

Documents about alzheimer-s-disease

• PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer's disease model.#213896NCBI PubMed Central
• Proteomic analysis in Alzheimer's disease and other dementias: a focus on sex-specific differences.#220848NCBI PubMed Central
• Feature fusion and WOA-GWO optimization for Alzheimer’s disease detection with sparse EEG channels.#221212NCBI PubMed Central
• Escherichia coli Nissle 1917 alleviates Alzheimer's disease in mice through OmpA-containing outer membrane vesicles.#222836NCBI PubMed Central
• APOE ε4 carriership status enhances age-related changes in Alzheimer’s disease plasma biomarkers concentrations#231420Europe PMC
• Beyond Inhibition: Rebalancing the Hsp90 Chaperone Network as a Therapeutic Strategy for Alzheimer’s Disease.#244352NCBI PubMed Central
• Identification of functional non-coding variants affecting Alzheimer's disease risk by Massively Parallel Reporter Assay#252828bioRxiv / medRxiv
• A data-driven Alzheimer's disease progression simulator for retrospective validation and prospective Phase III power design#252875bioRxiv / medRxiv
• Safety and short-term outcomes of lecanemab for Alzheimer's disease in China: a multicentre study.#260287NCBI PubMed Central
• Is there a cognitive measure of neurodegeneration for amyloid-Aβ-ratio probable Alzheimer's disease patients?#262904NCBI PubMed Central
• Tau topography subtypes account for clinical heterogeneity and longitudinal trajectories in early-onset Alzheimer's disease.#263033NCBI PubMed Central
• Improved Multiscale Structural Mapping with Supervertex Vision Transformer for the Detection of Alzheimer's Disease Neurodegeneration.#265271NCBI PubMed Central
• Neuropathological study of the effects of aducanumab anti-Aβ immunotherapy on patients with Alzheimer's disease.#288590NCBI PubMed Central
• Design of an artificial intelligence model to screen spontaneous speech to detect Alzheimer's Disease#314742Europe PMC
• Calibrating microglia states in Alzheimer's disease: decoding immune-metabolic networks and nano-targeted multicomponent therapies.#330671NCBI PubMed Central
• Combining β 2 -AR agonism with butyrylcholinesterase inhibition, a synergistic neuroprotective action against Alzheimer's disease#350562HAL (France)
• Alzheimer's disease neuroimaging signature aids identification of cognitive impairment in older adults with early-onset epilepsy#353175bioRxiv / medRxiv
• What Are the Potential Therapeutic Benefits of Targeting Blood-Borne Lipoproteins in the Treatment of Alzheimer's Disease?#367987NCBI PubMed Central
• Spatiotemporal dynamics of tau extent and load increase in Alzheimer's disease across four longitudinal cohorts.#380719NCBI PubMed Central
• Multiple sclerosis as a genetic risk factor for Alzheimer's disease: Insights from Mendelian randomisation.#385145NCBI PubMed Central
• Slow-wave sleep across the Alzheimer's disease continuum: cognitive trajectories and sex differences#387644Europe PMC
• Association between Alzheimer's disease and MHC-I antigen processing and presentation pathway: a narrative review.#402457NCBI PubMed Central
• Criterion-Referenced Sex-Specific Six-Minute Walk Distance Cut-Offs for Staging Alzheimer's Disease.#409129NCBI PubMed Central
• Omega-3 Fatty Acids and Alzheimer's Disease: Toward a New Understanding of Neuroprotective Mechanisms and Intervention Strategies.#409204NCBI PubMed Central
• Classifying Alzheimer's Disease Using Audio and Text-Based Representations of Speech#427506MIT Open Scholarship
• A randomized phase 1b/2 trial of ABBV-916 in adults with early Alzheimer's disease.#438942NCBI PubMed Central
• LSEAD: A Privacy-Preserving LLM-Based Speech Analysis Framework for Early Alzheimer's Disease Screening#440363arXiv CS
• Regional astrocyte dysregulation and altered glymphatic-related markers in Alzheimer's disease frontal cortex.#457459NCBI PubMed Central
• In Silico Evaluation Of The Iron Chelator Deferoxamine As A Potential Acetylcholinesterase (AcHe) Inhibitor For Alzheimer's Disease#467436AVESIS
• Divergent trends in Alzheimer's disease burden: a comparative analysis of the US and G20 nations.#472667NCBI PubMed Central
• A Biologically Constrained Continuous-Time Framework for Long-Horizon Cognition Forecasting in Alzheimer’s Disease#475666Europe PMC
• Novel cell markers with altered expression in brain aging and Alzheimer's disease: A review.#480823NCBI PubMed Central
• Aquaporin dysfunction and impaired brain interstitial fluid clearance in Alzheimer's disease - an integrative review.#636431NCBI PubMed Central
• Clinical impact of the Alzheimer's Disease Neuroimaging Initiative: A review of studies using ADNI data (2023 to June 2025).#28212NCBI PubMed Central
• Benzbromarone as a Novel Candidate for Preventing Alzheimer's Disease: Evidence From Real-World Data Screening and in Vitro Validation.#305025NCBI PubMed Central
• Standardized Comparison of Clinical, Cognitive, Genetic, Neuroimaging, and Fluid Biomarkers for Predicting 24-Month Progression from Mild Cognitive Impairment to Alzheimer's Disease#640150bioRxiv / medRxiv
• A Multidisciplinary Perspective on Research Participation in the Era of Post-Amyloid Disclosure and Disease-Modifying Therapies#289552OSF
• Biomarker-Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease-Modifying Treatments: A Consensus Statement by Belgian Experts.#422826NCBI PubMed Central
• Racial and ethnic differences in older adults’ willingness to be contacted about Alzheimer's disease research participation#491812eScholarship
• Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer’s disease#609426eScholarship
• Efeitos do programa AD-HOMEX nas funções cognitivas, no controle postural e desempenho funcional de idosos com doença de Alzheimer: um ensaio clínico randomizado e controlado#313285RI UFSCar
• Potential of ASCOT-Carer for evaluating the quality of life of family caregivers for patients with Alzheimer's disease in Japan.#154447NCBI PubMed Central
• Hierarchical-circular model of biological memory: a multilevel hypothesis for pathogenesis and allostatic integrity in Alzheimer's disease and related dementias.#354718NCBI PubMed Central
• Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer's disease continuum.#607NCBI PubMed Central
• Brain network dynamics determine tau presence while regional vulnerability governs tau load in Alzheimer’s disease#4852Europe PMC
• Diagnostic performance of salivary markers of Alzheimer's disease: A systematic review#5490Europe PMC
• Targeting of Itch by clomipramine or gene therapy improves cognitive defects related to Alzheimer's disease#5586Europe PMC
• APOE-stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease.#9004NCBI PubMed Central
• Evaluating the peripheral nervous system pathology of Alzheimer's disease utilizing a functional human NMJ microphysiological system.#28211NCBI PubMed Central
• Elevated plasma klotho levels attenuate Alzheimer's disease pathologies and cognitive decline in APOE ε4 carriers.#30862NCBI PubMed Central