alzheimer-s-disease

Documents about alzheimer-s-disease

• Cell Type-Specific Expression of p16, p21, and p53 Reveals Age-Dependent Glial Senescence in the App(NL-G-F) Mouse Model of Alzheimer's Disease.#13422NCBI PubMed Central
• Repeated low-intensity focused ultrasound induces microglial profile changes in the TgF344-AD rat model of Alzheimer’s disease#135544Unpaywall
• Evaluating MRI correlates of lifestyle-based dementia risk reduction: Results from the AgeWell.de imaging study#144948HAL (France)
• Cell-Type-Resolved Pseudobulk Classification Across Independent Cohorts Identifies Microglial PTPRG as a Transcriptional Hub in Alzheimer’s Disease#169066Unpaywall
• A Genome-wide Association Study of Alzheimer's Disease and Dementia in a Large Multi-ancestry Military Cohort Identifies Many New Dementia-Associated Loci#261184bioRxiv / medRxiv
• Age‐related increase in plasma p‐tau217 in amyloid‐beta–negative cognitively unimpaired individuals affects diagnostic interpretation#268316Europe PMC
• Age-related increase in plasma p-tau217 in amyloid-beta-negative cognitively unimpaired individuals affects diagnostic interpretation#273351Europe PMC
• Circuit modeling of neural activity ultra-slow fluctuations in the prefrontal cortex and associated pathologies#291641HAL (France)
• Plasma neurofilament light chain and regional brain atrophy mediate the association of neuropsychiatric symptoms with cognition in Alzheimer's disease: evidence from two population-based studies.#297134NCBI PubMed Central
• NavegApp, a serious game for assessing spatial cognition: Diagnostic accuracy in preclinical and prodromal Alzheimer’s disease#358726PLOS
• Development of a new episodic memory assessment tool (NEM): Preliminary data and clinical perspectives#395345HAL (France)
• Vitamin a modulates neurogenesis-associated pathways and cholinergic signaling in Alzheimer's disease: potential role of reactive astrocytes via NGN2/SOX-11 and SIRT-1.#406392NCBI PubMed Central
• The Substrate-Engine Model of Ferroptosis: Stage-Specific Targeting of Acyl-CoA Synthetase Long-Chain Family Member 4 and 5‑Lipoxygenase in Alzheimer's Disease.#469114NCBI PubMed Central
• Multidomain cognitive impairment, along with comorbidities and psychiatric hospitalizations, shorten survival time of patients with Alzheimer's disease dementia: A long term, naturalistic follow-up study.#483338NCBI PubMed Central
• Cross‐ancestry polygenic risk scores enhance Alzheimer's disease risk prediction in multiethnic cohorts#485002Europe PMC
• AI-Based Facial Emotion Analysis for Early and Differential Diagnosis of Dementia#644351IRIS
• Cellular Senescence of Patient-derived Fibroblasts Reveals the Mid-old Stage as a Critical Window for Transcriptomic Signatures Linked to Alzheimer's Disease Biomarkers and Classification.#143186NCBI PubMed Central
• The effects of the Multicultural Healthy Diet on cognitive decline and Alzheimer's disease risk: a phase II randomized controlled trial in middle-aged adults.#219114NCBI PubMed Central
• Dissecting medial temporal lobe from diencephalic sub-volumes: The amnesia dichotomy revisited#254014HAL (France)
• Self-reporting quality of life in mild-to-moderate Alzheimer's disease and Lewy body dementia: Comparing capability and health-focused measures using response process validation.#288553NCBI PubMed Central
• A novel writing to dictation test to investigate lexical and sublexical processes: Italian normative data and preliminary clinical feasibility in Mild Cognitive Impairment and Alzheimer's disease.#382369NCBI PubMed Central
• Exosomal gene-based predictive model and therapeutic target identification for Alzheimer’s disease: A bioinformatics analysis#385446PLOS
• Clinical characteristics of patients with Alzheimer's disease and caregiver burden, mental health, and sleep quality: A cross-sectional comparative study in psychiatric hospitals and nursing homes.#388623NCBI PubMed Central
• Unraveling the molecular Nexus of Alzheimer’s Disease and HIV encephalitis: The role of cellular senescence and transcriptional regulation#453129PLOS
• Disruptions of the diffusion tensor image analysis along the perivascular space index and dynamic functional connectivity across the Alzheimer's disease spectrum: Implications for cognitive impairment.#483438NCBI PubMed Central
• A novel peptide derived from vascular endothelial growth factor prevents amyloid beta aggregation and toxicity#630265HAL (France)
• Acupuncture-induced changes in locus coeruleus connectivity and memory improvement in patients with amnestic cognitive impairment#5373Europe PMC
• Mechanistic insights into the disaggregation of amyloid-β fibrils by EPPS via replica-exchange molecular dynamics simulations#125797Europe PMC
• Gain-of-function Modulation of TREM2 and its Impact on Amyloid-β and Tau Pathologies in Alzheimer's Disease: A Systematic Review and Meta-analysis of Animal Studies.#258013NCBI PubMed Central
• Development of Novel Inhibitors for Alzheimer's Disease from Erythrina variegata L. Extract-Derived Clusters Using Molecular Docking, QSAR Modeling, Quantum Chemical Calculations, and Molecular Dynamics Simulations.#358251NCBI PubMed Central
• Age‐related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome#408759HAL (France)
• Diagnostic utility and psychometric properties of the Technology Activities of Daily Living Questionnaire (T-ADLQ) in people with non-formally educated with Alzheimer's disease in Lima, Peru#416452Repositorio Universidad del Desarrollo
• Identification and validation of mitophagy and astrocyte-related molecular signature in the pathogenesis of Alzheimer's disease: evidence from ensemble learning-driven multi-omics and clinical validation.#439009NCBI PubMed Central
• Design and evaluation of a novel peptide-EV complex for targeted Alzheimer’s disease therapy#478479Figshare
• Predicting accumulation and age at onset of amyloid-β from genetic risk and resilience for Alzheimer's disease#485169Europe PMC
• Representations and practices of prevention in elderly populations: Investigating acceptance to participate in and adhesion to an intervention study for the prevention of Alzheimer's disease (accept study) — The need for a multidisciplinary approach#121820HAL (France)
• Effects of a 24-week resistance exercise program on Alzheimer's disease brain signatures in cognitively unimpaired older adults: a secondary analysis of the AGUEDA randomized controlled trial.#8958NCBI PubMed Central
• Retinal Microvascular Dysfunction Reflects Vascular and Alzheimer's‐Related Pathology in Dementia With Lewy Bodies#123237Europe PMC
• Combined home-delivered transcranial direct current stimulation and cognitive training in older adults with mild cognitive impairment due to Alzheimer's disease: a randomized, single-blind, sham-controlled trial.#220881NCBI PubMed Central
• Cobalt and titanium levels in the brain are associated with Alzheimer's disease pathology but not cognition: A study of older adults with and without total joint replacement.#269622NCBI PubMed Central
• White matter microstructural integrity as a key to effective propagation of gamma entrainment in humans#348037KOASAS: KAIST Open Access Self-Archiving System
• The use of religion, prayer, and faith to cope with the receipt of Alzheimer's disease risk information in a research context: A qualitative study of Latinos in NYC.#351417NCBI PubMed Central
• Longitudinal Metabolomic Profiling of Biogenic Amines in Plasma and CSF, and Their Correlation, Reveals Sex-Specific and Age Changes in TgF344 Alzheimer’s Disease Transgenic and Wildtype Rats#367247Europe PMC
• Local translation controls early reactive changes in perisynaptic astrocyte processes at pre-symptomatic stages of Alzheimer's disease#408698HAL (France)
• Higher Frontal Cortex Angiotensin Type 2 Receptor-Interacting Protein (ATIP) Levels Are Associated With a Lower Amyloid-Beta Burden in Postmortem Brains of Older Adults With Alzheimer's Disease.#625840NCBI PubMed Central
• Blood-based biomarkers of Alzheimer’s disease and neurodegeneration in an indigenous African cohort using both Simoa and NULISA platforms#635046Europe PMC
• Pathogenic tau in the mouse locus coeruleus produces noradrenergic hyperactivity and neuropsychiatric phenotypes reminiscent of early Alzheimer’s disease#635048Europe PMC
• Revising the ABIDE MCI to dementia prediction model for automated cerebrospinal fluid assays#8121HAL (France)
• Deciphering the molecular network of Trichostatin A in regulating Alzheimer’s disease screening of core genes and mechanistic investigation based on multidimensional bioinformatics and molecular simulation#130460Unpaywall
• Association between inflammatory biomarkers and the cognitive response to a multidomain intervention: secondary longitudinal analyses from the MAPT study#172978HAL (France)