alzheimer-s

Documents about alzheimer-s

• PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer's disease model.#213896NCBI PubMed Central
• Proteomic analysis in Alzheimer's disease and other dementias: a focus on sex-specific differences.#220848NCBI PubMed Central
• Feature fusion and WOA-GWO optimization for Alzheimer’s disease detection with sparse EEG channels.#221212NCBI PubMed Central
• Escherichia coli Nissle 1917 alleviates Alzheimer's disease in mice through OmpA-containing outer membrane vesicles.#222836NCBI PubMed Central
• APOE ε4 carriership status enhances age-related changes in Alzheimer’s disease plasma biomarkers concentrations#231420Europe PMC
• Beyond Inhibition: Rebalancing the Hsp90 Chaperone Network as a Therapeutic Strategy for Alzheimer’s Disease.#244352NCBI PubMed Central
• Identification of functional non-coding variants affecting Alzheimer's disease risk by Massively Parallel Reporter Assay#252828bioRxiv / medRxiv
• A data-driven Alzheimer's disease progression simulator for retrospective validation and prospective Phase III power design#252875bioRxiv / medRxiv
• Safety and short-term outcomes of lecanemab for Alzheimer's disease in China: a multicentre study.#260287NCBI PubMed Central
• Is there a cognitive measure of neurodegeneration for amyloid-Aβ-ratio probable Alzheimer's disease patients?#262904NCBI PubMed Central
• Tau topography subtypes account for clinical heterogeneity and longitudinal trajectories in early-onset Alzheimer's disease.#263033NCBI PubMed Central
• Improved Multiscale Structural Mapping with Supervertex Vision Transformer for the Detection of Alzheimer's Disease Neurodegeneration.#265271NCBI PubMed Central
• Study of the utility and impact of a plasma p‐tau181 Alzheimer's biomarker (SUITABLE).#265524NCBI PubMed Central
• Neuropathological study of the effects of aducanumab anti-Aβ immunotherapy on patients with Alzheimer's disease.#288590NCBI PubMed Central
• Design of an artificial intelligence model to screen spontaneous speech to detect Alzheimer's Disease#314742Europe PMC
• Calibrating microglia states in Alzheimer's disease: decoding immune-metabolic networks and nano-targeted multicomponent therapies.#330671NCBI PubMed Central
• Source-Free Active Learning for Adapting Alzheimer's Diagnostic Deep Learning Models Across Neuroimaging Cohorts.#338410NCBI PubMed Central
• Combining β 2 -AR agonism with butyrylcholinesterase inhibition, a synergistic neuroprotective action against Alzheimer's disease#350562HAL (France)
• Alzheimer's disease neuroimaging signature aids identification of cognitive impairment in older adults with early-onset epilepsy#353175bioRxiv / medRxiv
• What Are the Potential Therapeutic Benefits of Targeting Blood-Borne Lipoproteins in the Treatment of Alzheimer's Disease?#367987NCBI PubMed Central
• Spatiotemporal dynamics of tau extent and load increase in Alzheimer's disease across four longitudinal cohorts.#380719NCBI PubMed Central
• Multiple sclerosis as a genetic risk factor for Alzheimer's disease: Insights from Mendelian randomisation.#385145NCBI PubMed Central
• Slow-wave sleep across the Alzheimer's disease continuum: cognitive trajectories and sex differences#387644Europe PMC
• Association between Alzheimer's disease and MHC-I antigen processing and presentation pathway: a narrative review.#402457NCBI PubMed Central
• SuperAging is not the inverse of common-variant Alzheimer's risk: evidence across genetic ancestries.#402848NCBI PubMed Central
• Criterion-Referenced Sex-Specific Six-Minute Walk Distance Cut-Offs for Staging Alzheimer's Disease.#409129NCBI PubMed Central
• Omega-3 Fatty Acids and Alzheimer's Disease: Toward a New Understanding of Neuroprotective Mechanisms and Intervention Strategies.#409204NCBI PubMed Central
• Classifying Alzheimer's Disease Using Audio and Text-Based Representations of Speech#427506MIT Open Scholarship
• A randomized phase 1b/2 trial of ABBV-916 in adults with early Alzheimer's disease.#438942NCBI PubMed Central
• LSEAD: A Privacy-Preserving LLM-Based Speech Analysis Framework for Early Alzheimer's Disease Screening#440363arXiv CS
• Regional astrocyte dysregulation and altered glymphatic-related markers in Alzheimer's disease frontal cortex.#457459NCBI PubMed Central
• In Silico Evaluation Of The Iron Chelator Deferoxamine As A Potential Acetylcholinesterase (AcHe) Inhibitor For Alzheimer's Disease#467436AVESIS
• Divergent trends in Alzheimer's disease burden: a comparative analysis of the US and G20 nations.#472667NCBI PubMed Central
• A Biologically Constrained Continuous-Time Framework for Long-Horizon Cognition Forecasting in Alzheimer’s Disease#475666Europe PMC
• Novel cell markers with altered expression in brain aging and Alzheimer's disease: A review.#480823NCBI PubMed Central
• Predicting Four-Year's Alzheimer's Disease Onset Using Longitudinal Neurocognitive Tests and MRI Data Using Explainable Deep Convolutional Neural Networks.#9323NCBI PubMed Central
• Novel approach to early prediction of alzheimer's disease progression using integrated deep regulatory genetic neural network and optimized deep belief networks.#395912NCBI PubMed Central
• Racial and ethnic differences in older adults’ willingness to be contacted about Alzheimer's disease research participation#491812eScholarship
• A phase 2, randomized, multicenter, double-blind, placebo-controlled trial of S-adenosyl methionine in participants with mild cognitive impairment or dementia due to Alzheimer's disease.#14810NCBI PubMed Central
• Caregiver burden and quality of life associated with behavioral and psychological symptoms of Alzheimer's disease: A web-based cross-sectional survey study.#186074NCBI PubMed Central
• circPDE4B downregulation triggers GEMIN5‑dependent translational stress response and autophagy to reduce MAPT pathology#215368Europe PMC
• Higher physical activity levels mitigate synaptic protein loss and cognitive deterioration in aging and in Alzheimer's disease: a 10-year longitudinal study.#375195NCBI PubMed Central
• Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer's disease continuum.#607NCBI PubMed Central
• Brain network dynamics determine tau presence while regional vulnerability governs tau load in Alzheimer’s disease#4852Europe PMC
• Amyloid-linked versus age-driven copathologies in Alzheimer’s dementia: differential associations with APOE ε4#4883Europe PMC
• Diagnostic performance of salivary markers of Alzheimer's disease: A systematic review#5490Europe PMC
• Targeting of Itch by clomipramine or gene therapy improves cognitive defects related to Alzheimer's disease#5586Europe PMC
• APOE-stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease.#9004NCBI PubMed Central
• A brain-persistent DDR2-degrading antibody reverses Alzheimer's pathologies by restoring brain fluid dynamics and metabolic clearance#13916bioRxiv / medRxiv
• Evaluating the peripheral nervous system pathology of Alzheimer's disease utilizing a functional human NMJ microphysiological system.#28211NCBI PubMed Central